Age

45–75

Sex

ALL

Healthy volunteers

Not accepted

Previous diagnosis of asthma, other airway obstructive disease, sleep apnea syndrome, interstitial lung disease, chest wall disease or neuromuscular disease.
Apnea-hypopnea index \> 10/h
Morbid obesity (BMI \> 45 Kg/m2)
Previous diagnosis of ischaemic heart disease, cardiac failure, cirrhosis, chronic renal failure, rheumatoid arthritis or other inflammatory disease.

Effect of Noninvasive Ventilation on Physical Activity and Inflammation in COPD Patients