Continuous Glucose Monitoring and Insulin Pump Therapy in Diabetic Gastroparesis

Inclusion Criteria

• •Age 18 - 70 years old at registration
• •Type 1 or Type 2 diabetes mellitus for at least 2 years
• •Symptoms of gastroparesis (nausea, vomiting, early satiety, bloating, fullness, discomfort) for at least 1 year prior to registration
• •Gastroparesis Cardinal Symptom Index (GCSI) score of 18
• •Delayed gastric emptying on gastric scintigraphy within 1 year of registration, defined as greater than 60% retention at 2 hours or greater than 10% retention at 4 hours
• •Hemoglobin A1c of at least 8.0% at registration regardless of current therapy. Individuals already receiving diabetes therapy via an insulin pump will be eligible for study participation if, in the opinion of the investigators, he/she may acquire additional benefit from continuous glucose monitoring that might improve glycemic control
• •Normal upper endoscopy within 1 year of registration
• •No clinical or imaging evidence of obstruction
• •Successful mastering of use of CGMS during the run-in period