Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Akron Children's Hospital
Pulmonary hypertension is recognized as a significant cause of morbidity and mortality in patients with sickle cell disease. Doppler echocardiography is a recommended noninvasive screening tool for sickle cell disease patients with pulmonary hypertension. Brain natriuretic peptide levels have been found to be a possible serum screening marker. This research will offer the opportunity to determine if there is any possible relationship between magnitude of BNP concentration and degree of TRV, if it can be used as a screening test in SCD pediatric patients with PHT and form the basis for a future multicenter study
Age
7–21
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Male and Female any age
Diagnosis of SCD with PHT on echocardiogram
Controls must have a diagnosis of sickle cell disease without Pulmonary hypertension, age, gender and disease type match to subjects with pulmonary hypertension
Parent or Legal guardian willing to sign informed consent form
You may not be if
Abnormal echocardiograms not related to PHT
Parent or Legal guardian unwilling or unable to give written informed consent
