Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Imperial College London
With
Medical Research Council
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adult patient with COPD diagnosed according to GOLD criteria.
You may not be if
Clinically unstable patients (within one month of exacerbation), those with a permanent pacemaker (which is a contraindication to magnetic stimulation), or significant co-morbidity, patients with an accepted indication for ACE inhibition (left ventricular dysfunction, diabetes) or a contraindication such as renovascular disease; creatinine clearance (estimated) \<50); hypotension; use of anticoagulants (contra-indication to biopsy) or ACE-I or ATII receptor antagonists.
Allergy to ACE-inhibitors.
Pregnancy.
Patients will not be enrolled within three months of participation in a pulmonary rehabilitation program.
Clareo Health | Angiotensin-converting Enzyme (ACE)-Inhibition and Mechanisms of Skeletal Muscle Weakness in Chronic Obstructive Pulmonary Disease (COPD)
