Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Michigan
With
Renal Research Institute
Age
18–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Individuals eligible to participate in this study must meet all of the following criteria:
Willing and able to provide written, signed informed consent after the nature of the study has been explained, and prior to any research-related procedures.
Age ≥ 18 years and ≤ 85 years.
Willing and able to comply with all study procedures.
Patients with eGFR of 20 to 60 ml/min/173m2 by the abbreviated (4-variable) MDRD equation and a relatively stable clinical course.
Sitting systolic blood pressure ≥ 100 mmHg prior to study entry (to exclude people at risk from hypotension from dietary salt reduction).
You may not be if
Recent hospitalization (≤1 month) unless clearly for a minor elective procedure unlikely to interfere with BIA measurements. The final decision will be left to the site PI's discretion.
Any psychological condition (including alcoholism) that could interfere with the patient's ability to comply with the study protocol.
Subjects with baseline 24-hour urinary sodium excretion ≤100 mmol/day.
Amputation of a limb other than fingers or toes.
Pacemaker, defibrillator, implantable pump, artificial joint, pins, plates or other types of metal objects in the body (other than dental fillings).
Coronary stents or metal suture material in the heart.
Use of any investigational product or investigational medical device within 30 days prior to screening, or requirement for any investigational agent prior to completion of all scheduled study assessments.
Weight over 300 pounds (limitation for examination table).
Pregnancy or lactation.
Patients with kidney diseases known to be associated with salt wasting (see above).
Patients with atrial fibrillation as ambulatory blood pressure measurements may not be accurate in this setting.
Any condition that, in the view of the PI, places the subject at high risk of poor treatment compliance or of not completing the study.
