Clareo Health | AVAPERL1 Study: A Study of Avastin (Bevacizumab) With or Without Pemetrexed as Maintenance Therapy After Avastin in First Line in Patients With Non-Squamous Non-Small Cell Lung Cancer
AVAPERL1 Study: A Study of Avastin (Bevacizumab) With or Without Pemetrexed as Maintenance Therapy After Avastin in First Line in Patients With Non-Squamous Non-Small Cell Lung Cancer
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Keep this study
Lead
Hoffmann-La Roche
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
adults \>/=18 years of age
inoperable, locally advanced, metastatic or recurrent non-squamous non-small cell lung cancer (NSCLC)
at least 1 measurable lesion meeting RECIST criteria
ECOG performance status 0-2
adequate hematological, liver and renal function
You may not be if
prior chemotherapy or treatment with another systemic anti-cancer agent
malignancies other than NSCLC within 5 years prior to randomization, except for adequately treated carcinoma in situ of the cervix, basal or squamous cell skin cancer, localized prostate cancer or DCIS
evidence of tumor invading major blood vessels
current or recent use of aspirin (\>325mg/day) or full-dose anticoagulants or thrombolytic agents for therapeutic purposes