Women aged between 18 and 70

Patient with life condition \< 2 (WHO scale)

One-sided breast adenocarcinoma with a histological evidence (all type)

Clinical presentation which allowed a complete surgery with healthy limits

Absence of metastasis detectable at clinical examination or radiology

Histological evidence for homolateral axillary ganglionic invasion, whatever is the number of node invaded (N \> 1)

The beginning of the chemotherapy within 6 weeks following the primary surgery

Utilization of Genomic Signature as Decision-making for Adjuvant Treatment of Breast Cancer