Randomized Trial of Interventions to Improve Warfarin Adherence

You may be eligible if

• The study population will include all patients at the study sites who:
• 1. are in the maintenance phase of their warfarin treatment (defined using the standard method as the period of time following 2 consecutive visits, at least 7 days apart, of stable target INR after initiation of the drug)
• 2. whose providers indicate are expected to stay on treatment for at least 6 months
• 3. have a target INR of 2 to 3.5
• 4. had at least one INR out of the participant's target range within 90 days prior to enrollment (excluding the baseline visit) and/or INR at the baseline visit was below the participant's target range
• 5. have a working analog telephone line.
• Of note, patients do not have to be within their target INR range to enroll; we specifically want to include those who are below the target range at the time of study entry because they may be the patients most likely to be non-adherent.
• 1. have an INR at screening above the target range
• 2. are less than 18 years of age and cannot or will not give consent
• 3. cannot read above a 6th grade reading level
• 4. are enrolled in a clinical trial of warfarin therapy
• 5. are unable to adequately follow study procedures