Adenosine Dual Source Computed Tomography (CT) Versus Adenosine Single Photon Emission Computed Tomography (SPECT)

Exclusion Criteria

• •Patients being referred to invasive coronary angiography will not be included in this pilot
• •Caffeine intake within the 24 hours prior to adenosine stress testing
• •Pregnancy (known or suspected)
• •Intolerance or contraindication to adenosine (severe Asthma…)
• •Intake of methylxanthine containing medications such as theophylline that have not been withdrawn and would interfere with the effectiveness of adenosine.
• •Unstable coronary syndromes
• •Uncontrolled congestive cardiac failure or cardiogenic shock
• •Uncontrolled hypertension with resting BP \> 200/110
• •More than 30 days between the Adeno-SPECT and the Adeno-DSCT
• •Revascularization (percutaneous coronary intervention or coronary artery bypass graft surgery) between the Adeno-SPECT and the Adeno-DSCT
• •Change in clinical status as determined by the investigator
• •Inability to be on same medication regime 24 hrs prior to Adeno-SPECT and Adeno DSCT
• •Patients with chronic renal failure (C.C.T. \< 60 ml/m2/sec)
• •Patients with allergy to contrast iodinated media
• •Congestive heart failure
• •History of thromboembolic disorders
• •Multiple myeloma
• •Hyperthyroidism
• •Pheochromocytoma
• •Atrial fibrillation
• •Inability to perform breath hold for 12 seconds
• •Pilot 2:
• •All inclusions/exclusions are the same as Pilot 1, WITH THE ADDITION OF:
• •Patients with contraindications to coronary angiography