Finding studies
Finding studies
Take this into the appointment.
Saves the questions and what to expect into your notes, next to the visit they belong to.
Lead
University of Arizona
With
OBJECTIVES: Primary * To evaluate the efficacy of acupuncture in reducing pain, defined by improvements in overall WOMAC score at 6 weeks, in post-menopausal women with breast cancer and aromatase inhibitor (AI)-associated arthralgia. Secondary * To identify biologic correlates to acupuncture efficacy in this specific syndrome of AI-associated pain. * To evaluate the efficacy of acupuncture in these patients. OUTLINE: Patients are randomized to 1 of 2 treatment arms: * Arm I: Patients undergo acupuncture for 20-30 minutes, on the appropriate pain points on the anterior portion of the body alternating with posterior portion of the body, thrice weekly for 2 weeks and then twice weekly for 3 weeks. * Arm II: Patients receive standard-of-care analgesics (i.e., NSAIDs, narcotics, acetaminophen, or other) for 5 weeks. Patients not responding to analgesia may cross over to arm I. Patients are assessed periodically for improvement in pain, menopausal symptoms, and overall quality of life by the WOMAC, Brief Pain Inventory, and FACT-ES questionnaires. Blood samples are collected at baseline, 6 weeks, 3 months, and 6 months for biomarker studies of brain-derived neurotrophic factor and serotonin-transporter gene polymorphisms levels by ELISA. After completion of study therapy, patients are followed at 1 week, 6 weeks, 3 months, and 6 months.
Age
Any age
Sex
FEMALE
Healthy volunteers
Not accepted
