Objective:
This protocol will test the hypothesis that the 3-Hz spike-wave discharges seen in absence epilepsy originate in the thalamus. We will use an emerging modality, magnetoencephalograpy (MEG), to test this hypothesis.
Study Population:
33 patients with absence seizures.
Design:
This is a non-invasive imaging study that involves a 275-channel whole head MEG recording and a structural MRI for co-registration of MEG data.
Outcome Measure:
The primary outcome measure is the source localization of spike-wave discharges on magnetoencephalography.
