Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Pittsburgh
Age
18–50
Sex
MALE
Healthy volunteers
Accepted
You may be eligible if
Male OIF/OEF returnees between the ages of 18 and 45 years old
Combat Exposure Scale score \> 17
Not taking medications known to affect sleep or wake function for at least 2 weeks (6 weeks for fluoxetine).
No history of trauma before age 18
Meet diagnostic criteria for current PTSD according to the CAPS-1
CAPS-1 score is less than 80
Total CAPS-1 scores \< 17
Does not meet criteria for PTSD
You may not be if
Trauma occurred less than 3 months prior to study entry
CES score \< 17
Taking medications known to affect sleep and / or brain glucose metabolism
Current diagnosis of depression as determined by the SCID or BDI score \> 13
History of psychotic or bipolar disorder
Current history (within 3 months) of substance or alcohol abuse as determined by the SCID
Positive alcohol blood test at screening or during the PET protocol
Significant or unstable acute or chronic medical conditions
Other current sleep disorders, such as insufficient sleep syndrome, delayed sleep phase syndrome, narcolepsy, restless legs syndrome, periodic leg movement disorder, obstructive sleep apnea, and current night shift work, suspected during the structured interview. Individuals who are found to have a apnea-hypopnea index (AHI) \> 10 or an index of periodic leg movements with arousal \> 15 will be excluded.
Presence of implanted devices such as cardiac pacemaker, aneurysm clip, ear implant, shrapnel, neurostimulators or other metal devices
Fear of closed spaces
Previous radiation. Due to the risk of radiation exposure, we will exclude subjects who have had PET scans or other radiotracer exposure in the previous year.
History of open head injury.
Clareo Health | Neurobiological Correlates of Post Traumatic Stress Disorder (PTSD) During Rapid Eye Movement (REM) Sleep
