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Clareo Health | Niacin and Endothelial Function in Early CKD

Niacin and Endothelial Function in Early CKD

NCT00852969·1 site·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Lead

Tufts Medical Center

With

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Age

21–80

Sex

ALL

Healthy volunteers

Not accepted

You may be eligible if

Diagnosis of CKD Stage 2 (GFR \>60 and microalbuminuria/proteinuria) and Stage 3-4 (GFR 15-30)
HDL-cholesterol \<50 for men and \<55 for women
If taking a statin, stable dose for past one month
Glucose \<200 mg/dL and HbA1c \<9%
Transplant recipients who are in stage 2-3 CKD; 1-year post transplant; and have had no rejection episodes in the 6-months prior to study entry

You may not be if

Hospitalization within prior 3 months
Any of the following conditions:
* uncontrolled peptic ulcer disease
* active liver disease OR abnormal SGOT/SGPT
* history of adverse reaction to niacin
* contra-indication to aspirin
* concurrent fibrate therapy
* history of gout
* serum phosphorus levels below 2.7mg/dl
Nursing
Pregnancy

The record

StatusCompleted

PhasePhase 4

Taking part30

StartedAug 2008

UpdatedMay 6, 2014

Conditions

Chronic Kidney Disease

Where1

Tufts Medical Center
Boston, Massachusetts, United States