Clareo Health | Pharmacodynamics and Non-Clinical Inferiority of Heparin Sodium (Cristália) Compared With the Product Liquemine (Roche) in Chronic Renal Failure
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Azidus Brasil
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adults of both sexes, regardless of color or social class
Age over 18 years with a good clinical medical criteria
Patients who agreed to participate and signed the Informed Consent
Insufficient patients in chronic renal dialysis schedule (3 times per week)
Patients with creatinine clearance \<30ml/min
Patients with indication for anticoagulation during hemodialysis
You may not be if
Patients with sensitivity to heparin sodium;
Patients with hypersensitivity to benzyl alcohol
Patients with a history of bleeding or illness that can change the blood coagulation aggravate or terminate the clinical picture, such as tables of gastric ulcer
Patients with a history of peptic ulcer
Patients with body mass index greater than 30
Cancer patients because of the possibility of compromising the function of the variable coagulation
Patients in period of pregnancy or after delivery
Patients with genetic abnormality of the clotting system
Polytraumatized patients
Patients using glucocorticoids for at least 1 month
Patients using other anticoagulants
Patients with high rate of bleeding
Patients undergoing any surgery performed less than 15 days due to the risk of training of hematoma at the site of surgery
Hypertension above 140/90 mmHg
Patients using medications that could affect hemostasis
Patients using the following medicines: hormonal anti not including Ketorolac; Dextran 40, ticlopidine and clopidogrel, systemic glucocorticoids, thrombolytic agents and anticoagulants and other antiplatelet agents, including antagonists of glycoprotein IIb / IIIa.
