Nuclear Factor Kappa-B (NFKB1) Polymorphism and Organ Injury After Cardiac Surgery

Exclusion Criteria

• •malignant tumor
• •autoimmune disease, immunodeficiency or immunosuppressive therapy
• •chronic renal disease (glomerular filtration rate \< 60ml/(min•1.73m2)) or liver dysfunction (Child Pugh classification\>A)
• •COPD, tuberculosis or other chronic pulmonary diseases
• •anemia with hemoglobin lower than 90mmHg
• •bleeding disorders
• •postoperative pericardial tamponade requiring re-operation
• •postoperative low cardiac output syndrome or acute pulmonary edema after left cardiac failure.