Circadian Ocular Perfusion Pressure and Ocular Blood Flow

Exclusion Criteria

• •Female of child-bearing potential if pregnant, lactating, or not using highly effective birth control measures.
• •Severe central visual field loss in either eye.
• •Previous glaucoma surgery in the study eye.
• •Intraocular surgery in the study eye within 3 months prior to the Screening Visit.
• •Wears contact lenses.
• •Allergy/hypersensitivity to study medication.
• •Cannot safely discontinue use of glucocorticoid medication.
• •Uses medication that could affect IOP or blood pressure.
• •Recent use of high-dose aspirin.
• •Bronchial asthma or severe chronic obstructive pulmonary disease.
• •Diabetic retinopathy.
• •Any abnormality preventing reliable tonometry.
• •Any severe illness or condition unsuitable for the study, in the opinion of the investigator.