Diabetes Dietary Study- Low Carbohydrate and Low-Fat Diets in Type 2 Diabetes

Exclusion Criteria

• •Age \> 65
• •Weight \>280 lb
• •Health conditions that may interfere with study participation or for which the study interventions may be contraindicated. These include: kidney stones or kidney disease (creatinine \> 1.3 and 1.5 mg/dL for females and males, respectively; proteinuria \> 300 ug/g creatinine); liver or gall bladder disease; significant heart disease (myocardial infarction in the past six months, prior or current evidence of congestive heart failure, other evidence of left ventricular (LV) dysfunction) or other indices of active cardiac abnormalities, (angina, electrocardiogram evidence of ischemia or transmural myocardial infarction), significant anemia; and cancer (other than effectively treated non melanomatous skin cancer and surgically treated cervical cancer in situ).
• •Current hypokalemia defined as serum potassium levels \<3.5 mg/dL.
• •Osteoporosis
• •Type 1 diabetes (history of ketoacidosis or undetectable fasting C-peptide levels)
• •History of severe or repeated hypoglycemia, or hypoglycemia unawareness. Lack of recourse to another person in the immediate vicinity in the unlikely event that they require outside assistance for severe hypoglycemia.
• •Triglyceride levels \> 400 mg/dL.
• •Inability or unwillingness to comply with any aspects of the dietary and research protocol.
• •Weight changes \> 10 lbs in the past three months.
• •History of binge eating disorder or other eating disorders.
• •Pregnancy or intention to become pregnant in the next 12 months.
• •Current oral hypoglycemic medication that raises the blood insulin level