Hand Transplantation for the Reconstruction of Below the Elbow Amputations

Exclusion Criteria

• •Any condition that precludes serial follow-up.
• •Any active malignancy or any history of a hematogenous malignancy or lymphoma. Patients with primary, cutaneous basal cell or squamous cell cancers may be enrolled providing these are appropriately eliminated prior to transplant. For amputations due to malignancy, 5 years recurrence free survival will be required prior to enrollment.
• •Any known immunodeficiency syndrome.
• •Inability or unwillingness to comply with protocol monitoring and therapy, including, among others, a history of noncompliance, circumstances where compliance with protocol requirements is not feasible due to living conditions, travel restrictions, access to urgent medical services
• •Pregnancy or unwillingness to practice birth control methods during the first year of the study.
• •Unwillingness to undergo blood transfusion if clinically indicated