High-dose Cytarabine/Mitoxantrone Followed by Autotransplantation for t-MDS/t-AML

Inclusion Criteria

• •Patients must have received cytotoxic chemotherapy,radiation,or a drug known to affect the properties of DNA or cell growth for some condition other than acute myeloid leukemia prior to diagnosis.
• •Patients must have t-MDS/t-AML
• •To be eligible for allogeneic transplantation, patients must have a suitable donor who is HLA compatible.
• •Patients must be over the age of 10.
• •Patients must be reviewed and discussed at the Leukemia and Transplant Conferences of the Section of Hematology/Oncology.