Vitamin D Repletion in Chronic Kidney Disease

Exclusion Criteria

• •Serum calcium level \>10.5 mg/dl
• •Serum phosphorus level \> 5.5 mg/dl
• •Serum PTH level \< 35 pg/ml
• •Active infection including HIV, Hepatitis B or C
• •History of recent acute infection ( within 1 month)
• •Gastrointestinal disease resulting in significant GI dysfunction or malabsorption
• •Hgb\< 10 g/dL
• •Current use of Coumadin
• •Current use of Vitamin D \>400 IU/day
• •Current use of systemic steroids or other immunosuppressants
• •History of malignancy not in remission (\>6 months)
• •History of current ethanol abuse or illicit drug use
• •History of significant emotional disorder within the past 5 years
• •Participation in an investigational drug study within one month of screening
• •Have any other condition, which in the opinion of the investigator, should prohibit the participation in the study