Curcumin in Rheumatoid Arthritis

Inclusion Criteria

• •1. Age ≥ 18 years; read and understand English
• •2. Stable dose of non-steroidal anti-inflammatory agents (NSAID) for ≥ 2 weeks.
• •3. Oral prednisone or equivalent ≤ 10 mg daily and stable dose for ≥ 2 weeks(and must be kept stable throughout the duration of the protocol).
• •* ESR \> 20 mm/hr, or CRP \> 0.8 mg/dl
• •4. May be using any of the following DMARDs: methotrexate, sulfasalazine, hydroxychloroquine or leflunomide. If using any of these DMARDs must be using them for ≥ 12 weeks and stable dose for ≥ 4 weeks. If using other DMARD, or DMARD combinations, these additional or other DMARDs must be stopped for ≥ 4 weeks before baseline visit. May also participate if patient not on DMARD,
• •5. Subjects must be diagnosed with rheumatoid arthritis based on the revised American College of Rheumatology criteria:Presence of \> swollen and \> 6 tender joint count (28 joint count), and either ESR \> 20 mm/hr or CRP \> 0.8 mg/dl