Study of Occipital Nerve Stimulation for Drug Refractory Migraine

Exclusion Criteria

• •Have onset of headache after age 50;
• •Are current substance abusers (including alcohol and illicit drugs);
• •Have a significant psychiatric disorder;
• •Have previously been treated with occipital nerve stimulation (either temporary trial or permanent implant);
• •Have had nerve stimulation for pain relief.
• •Have had an injection of botulinum toxin in the head or neck within 6 months prior to enrollment;
• •Have previously undergone destructive ganglionectomy affecting C2/C3 occipital and/or trigeminal distribution or have an occipital blockade or radiofrequency procedure currently in effect.
• •Have a condition currently requiring or likely to require the use of MRI or diathermy;
• •Have an active implantable device;
• •Are pregnant or lactating or planning to become pregnant in the next 14 months;
• •Have participated in any drug or device trial in the last 4 weeks or plant to participate in any other study during the next 14 months.