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Tanezumab in Osteoarthritis of the Knee | Clinical Trials | Clareo Health

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COMPLETEDPhase 3NCT00733902

Tanezumab in Osteoarthritis of the Knee

Test the efficacy and safety of 3 doses in Osteoarthritis of the knee in patients.

Lead sponsor: Pfizer•82 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Pfizer

Age

18 - 99 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Osteoarthritis of the knee according to ACR criteria with a Kellgren-Lawrence x-ray grade of 2.
•Unwilling or unable to take non-opiate pain medications, for whom non-opiate pain medications have not provided adequate pain relief or are candidates for knee injections arthroplasty or replace surgery.
•Pain level and function levels as required by the protocol at Screening and Baseline.
•Willing to discontinue pain medications (acetaminophen will be permitted up to a certain level) before and during the study.
•Must agree to the contraceptive requirements of the protocol if applicable.
•Must agree to the treatment plan, scheduled visits, and procedures of the protocol.

Exclusion Criteria

•Pregnancy or intent to become pregnant during the study
•BMI greater than 39
•other severe pain, significant cardiac, neurological or psychological conditions, or above the protocol limits for laboratory and blood pressure results

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 22, 2021Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE3

Enrollment697

Start dateSep 2008

Last updatedMar 22, 2021

Condition

Arthritis Osteoarthritis

Locations shown

Arizona Research Center, Inc.

Phoenix, Arizona

Clinical Research Center of Connecticut

Danbury, Connecticut

Stamford Therapeutics Consortium

Stamford, Connecticut

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 22, 2021Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions