Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
New York State Psychiatric Institute
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Primary DSM-IV Diagnosis of OCD
Currently on a stable and adequate dose of SRI (or history of prior SRI or CBT treatment meeting criteria for adequate trial)
Patients not currently receiving an SRI or CBT will be included if they have undergone a prior SRI or CBT trial and they report no interest in pursuing another DRI or CBT trial at this time. Patients who have been on SRIs in the past must be free of SRIs for at least 6 weeks prior to participation
Y-BOCS score of greater or equal to 16
Physically health and females must be using effective contraception
Sufficient severity of symptoms to warrant additional augmentation treatment
Able to provide consent
You may not be if
Ongoing treatment with other antibiotics and/or Accutane. Patients with lupus erythematosus
Patients planning to start CBT during the study period or those who have begun CBT within the past 8 weeks
Presence of psychotic symptoms or lifetime history of schizophrenia, bipolar disorder or other psychotic disorder
Current major depressive disorder (patients must be free of the disorder for 3 months prior to enrollment). HAM-D must be \<18.
Judged clinically to be at risk of suicide (suicidal ideation, severe depression or other factors
Current eating disorder
Severe renal insufficiency
Documented history of hypersensitivity or intolerance to tetracycline antibiotics
Concomitant use of anti-coagulant drugs, antacids, iron, calcium, magnesium, aluminum, zinc sales. Note:Concomitant psychotropic medications such as antipsychotics and benzodiazepines will be permitted as long as they have been stable for at least 4 weeks and remain stable during the course of the study.
Current ETOH/drug abuse or dependence disorder of dependency in the past 3 months
Female patients who are either pregnant or nursing
