Hypothalamic Functional Magnetic Resonance Imaging (fMRI) Response to Nutrients

Exclusion Criteria

• •Those with a major medical illness or who require prescription medication, including: cancer, coronary artery disease, hypertension, and diabetes.
• •Subjects taking psychiatric or centrally-acting (CNS) medications, or who are diagnosed with a psychiatric or neurological illness, including: depression, anorexia, bulimia, and seizure disorder.
• •Subjects who have lost weight as a result of dieting, pharmacological treatment, or bariatric surgery.
• •Weight \> 350 lbs or girth \> 60 inches (the limits of the MR machine)
• •Exercise \> 30 minutes, 3 times a week.
• •Alcohol consumption \> 2 drinks / day.
• •Weight \> 300 lbs (150 kg) (weight limit for MR machine).
• •Blood glucose \> 100 mg/dL, abnormal creatinine or liver function tests.
• •Illicit drug use.
• •Pregnancy.
• •Extreme dietary habits as determined by a GCRC nutritionist: very high or low dietary carbohydrate, protein, or fat intakes.
• •Those with a contraindication to exposure to strong magnetic fields: presence of metal in the body such as body piercing, shrapnel, cardiac pacemakers or aneurysm clips.
• •Those with claustrophobia.