History of keratoconjunctivitis, open or closed angle glaucoma, or "dry eye" disease.

New York Heart Association (NYHA) Grade II or greater congestive heart failure.

History of myocardial infarction within 6 months prior to Day 1.

Presence of \>/= Grade 2 peripheral neuropathy.

Known presence of central nervous system or brain metastases.

Prior therapy with a conjugated or unconjugated maytansine derivative.

A Phase I Study of BIIB015 in Relapsed/Refractory Solid Tumors