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COMPLETEDNANCT00634907

Prospective Genotyping For Total Hip or Knee Replacement Patients Receiving Warfarin (Coumadin)

Several human genes affect how medications are metabolized by the body. It is believed that knowledge of variations of these genes can help health care providers better manage an anticoagulation medic...

Lead sponsor: Gwen McMillin•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Gwen McMillin

This study was completed in 2008 and was published. Consult the citation link for more details.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Participants were otherwise healthy adults (≥ 18 years of age) who were planning total hip or knee replacement or revision surgery at the University of Utah Hospital, and scheduled a pre-operative office visit at the University of Utah Orthopaedic Center.

Exclusion Criteria

•Blood transfusion in previous two weeks
•Participant is already taking warfarin
•Pre-operative INR \> 4.0
•Pre-operative bilirubin \> 2.4 mg/dL
•Current active cancer diagnosis with ongoing treatment
•Concomitant medications known to exert a major interaction with warfarin such as septra, metronidazole, tramadol, amiodarone, ciprofloxacin, or cimetidine.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 8, 2017Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment263

Start dateSep 2006

Last updatedJun 8, 2017

Condition

Venous Thromboembolism Bleeding

Locations shown

University of Utah Health Care

Salt Lake City, Utah

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 8, 2017Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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