Symptoms of current depressive episode for less than 30 days or more than 2 years

Mild depression, as measured by standard clinical research scales

Significant suicide risk

Lack of sexual activity (including masturbation)

Other psychiatric conditions that would obscure the results of the study

History of failure to respond to antidepressant treatment

Pregnancy or breast-feeding

An Eight-week Study of Saredutant and Paroxetine as Combination Treatment for Major Depressive Disorder