Lead Sponsor

University of Zurich

Collaborators

University Hospital of Psychiatry, Department Neuropsychopharmacology and Brain Imaging
H. Lundbeck A/S

Age

18 - 40 years

Sex

ALL

Healthy Volunteers

Yes

•Schizophrenia according to DSM IV
•Selected and treated in respect of the SPC (20 mg Serdolect max. and population at risk will be excluded)

•DSM IV Axis I disorders other than schizophrenia: Substance-dependence (excepting nicotine-dependence and substance-abuse), recent (2 months) DSM IV diagnosis according to DIA-X of a major affective, anxiety disorder, eating-disorder.
•DSM IV Axis II disorders: Lifetime DSM IV diagnosis of personality disorder.
•ECG: QTc-interval \>450 msec.
•Systolic blood pressure \<100 mmHg
•Bradycardia (Hf \< 50/Min) und Arrhythmias
•Hypokalemia or Hypomagnesemia