A Study of Efficacy of New Doses of Xolair to Protect From Allergen Challenge in Groups of Asthma Patients Defined by IgE Levels

Exclusion Criteria

• •Current active smokers
• •Patients who have been hospitalized or had emergency treatment for an asthma attack in the 12 months prior to study start
• •History of bleeding disorders
• •History of drug allergy
• •Pregnant women or nursing mothers
• •Females of childbearing potential, regardless of whether or not sexually active, if they are not using a reliable form of contraception (surgical contraception or double barrier methods (to be continued for at least two months following last dose) are acceptable).
• •Sexually active males who have not been sterilized and are not using a condom
• •History of immunocompromise, including a positive HIV
• •A positive Hepatitis B surface antigen (HBsAg) or Hepatitis C test result.
• •History of drug or alcohol abuse within 12 months of study start