Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)

This is a phase 2, multicenter, randomized, double-blind placebo-controlled, parallel group study to determine the persistence of the effect of SNP on blood pressure and to assess the potential for rebound hypertension associated with prolonged infusion in pediatric subjects. The primary endpoint is the change in MAP during the Blinded Study Drug Administration Phase in the absence of other stimuli.