Impact of Trans Fatty Acids From Natural and Industrial Origin in the Induction of Insulin Resistance Development

Exclusion Criteria

• •Reported food allergies
• •Currently participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of this study
• •Hepatic or renal impairments
• •Positive serologies to HIV or HCV, determined on blood sample
• •pregnant or presently attempting to get pregnant or menopause or lactating Blood donation done less than 2 months before the start of the study
• •Chronic pathologies: diabetes, hypertriglyceridemia, hypertension, cardiovascular diseases, chronic inflammatory diseases
• •Intestine, cardiovascular, kidney and cancer pathologies in the last 5 years
• •Previous heavy intestine surgery (except appendicectomy)
• •Previous medical and/or surgery judged by the investigator as incompatible with this study
• •High variation (\> 5%) of body weight during the last 3 months
• •Consuming nutritional supplements which could interfered with lipid metabolism (fish oil capsule, vitamins, soja lecithins,…)
• •Heavy consumer of alcohol
• •Smoker or ex-smoker who stopped smoking less than 1 month before V0 (more than 5 cigarettes/dy).
• •Practising intensive physical exercise (\> 5 h per week)
• •Vegetarian or vegan
• •Being under someone's supervision
• •Refusal to be registered on the National Volunteers Data file
• •Disliking butter, margarine, cheese, biscuits and/or vegetable oil
• •Dietary habits unreliable to controlled food intake
• •Being in exclusion on the National Volunteers Data file