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COMPLETEDNCT00613587

Roflumilast In-Vitro Basophil Release

This study is looking for allergic asthmatics. Lung and allergy testing will be done to verify. If qualified, blood will be drawn for laboratory studies.

Lead sponsor: Creighton University•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Creighton University

Collaborators

Takeda

Non-smoking allergic asthmatics will be verified using pulmonary function, skin prick testing, exhaled nitric oxide and serum IgE. If qualified, blood will be drawn, treated with study medication and then stimulated with the allergen to which the subject is allergic. Mediators including Histamine, IL-13, IL-4, and leukotrienes will be measured.

Age

19 - 65 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Age 19 and above Allergic Asthma Serum IgE greater than 30iu/ml Exhaled Nitric Oxide greater than 17ppb

Exclusion Criteria

•smoking history

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: October 10, 2012Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment15

Start dateAug 2007

Last updatedOct 10, 2012

Condition

Locations shown

Creighton University Medical Center

Omaha, Nebraska

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 10, 2012Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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