Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
National Institute of Neurological Disorders and Stroke (NINDS)
Objectives: 1) to attempt to detect specific patterns of hippocampal injury in patients with temporal lobe epilepsy that may be associated with HHV-6B infection; 2) To attempt to detect evidence for persistent HHV6 infection in CSF in patients with refractory temporal lobe epilepsy. 3) to obtain preliminary pilot data on the ability of high resolution structural to detect abnormalities in epilepsy patients not seen with standard scanners.
Study Population: 45 patients with localization-related epilepsy; 45 healthy volunteers
Design: 1) imaging with a 7T MRI magnetic resonance scanner; 2) Lumbar puncture. 3) blood sampling
Main outcome measure: 1) Detection of evidence for HHV6 infection in CSF
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Patients will be avaluated for participation under screening protocol 01-N-0139.
Patients
Male and female subjects age 18 to 55
Subjects with seizures uncontrolled by antiepileptic drugs
Subjects with no other illnesses, or taking other substances or medicines that could interfere with the study
Healthy Controls
Male and female subjects age 18 to 55.
You may not be if
Patient
Subjects who are pregnant or breast feeding.
Subjects with any medical condition that could interfere with the study.
Subjects who are taking drugs that significantly reduce blood clotting such as Coumadin or Warfarin.
Healthy Volunteers
Subjects who are pregnant or breast feeding
Subjects who have any medical condition or be taking any substance or medication that could interfere with the study
Subjects who are taking drugs that significantly reduce blood cloting such as Coumadin or Warfarin
