Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Icahn School of Medicine at Mount Sinai
With
Endo USA Inc., a Keenova Therapeutics Company
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age of 18 to no upper limit
Chronic pain of nociceptive, neuropathic, or mixed origin
Patients with chronic non cancer pain
Ongoing chronic opioid treatment with either oral morphine or oxycodone (long term - more than 3 months of at least a total daily opioid dose of 60 mg morphine or of 30 mg oxycodone)
Pain of moderate intensity (\>4, on the numerical scale 0-10) despite ongoing opioid therapy\>
Non-pregnant, non-lactating women
Sufficient language skills to communicate with research staff
You may not be if
Clinically significant respiratory, renal, hepatic, or cardiac disease.
Documented diagnosis of sleep apnea (the study physician may exclude patients who present with clinical features and complaints suggestive of a diagnosis of probable sleep apnea)
History of illicit drug or alcohol dependence or abuse, abnormal drug taking / seeking behaviors
Severe depression (\> 26 on the BDI)
Patients who exhibit a score on the Mini Mental Status Exam (MMSE) of 26 or less. (The range of scores for mild dementia is 21-26 on the MMSE).
Workman compensation, current or pending medical-legal litigation
Hypersensitivity to study medication (oxymorphone)
