A Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemia

Exclusion Criteria

• •Current clinically significant medical comorbidities, which may substantially compromise subject safety, or expose them to undue risk, or interfere significantly with study procedures and which, in the opinion of the Investigator, makes the subject unsuitable for inclusion in the study.
• •Body Mass Index (BMI) \<= 16.0 kg/m2 or =\>40.0 kg/m2.
• •Current or a history of significant gastrointestinal motility problems
• •Positive test for HIV 1 and 2 antibodies.
• •History of substance or alcohol abuse within the last year.
• •Seizure disorders.
• •History of drug or other allergy.
• •Temporary catheter with active signs of inflammation or infection.
• •The subject has participated in a clinical study with any experimental medication (with the exception of MCI-196 PIII studies) in the last 30days or experimental biological product within the 90 days prior to signing of informed consent form.