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COMPLETEDNANCT00510588

Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease

Chronic inflammatory activation in fat tissue can be the link between adiposity and an increased risk for atherosclerosis. Aim of the study is to investigate how molecular alterations in fat tissue ca...

Lead sponsor: University of Leipzig•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of Leipzig

Age

35 - 75 years

Sex

MALE

Healthy Volunteers

No

Inclusion Criteria

•either impaired glucose tolerance (2-h plasma glucose concentration \>7.8 and \<11.1 mmol/L during an oral glucose tolerance test) or impaired fasting glucose (fasting glucose concentration \>6.0 and \<7.0 mmol/L)
•coronary artery disease determined by coronary angiography
•BMI \> 25
•male patients aged 35-75 years

Exclusion Criteria

•diabetes mellitus type 1
•diabetes mellitus type 2 in combination with glycosylates hemoglobin \>6.0%, previous medication with oral antidiabetic agents or insulin, fasting plasma glucose concentration \> 11.0 mmol/L
•unstable angina pectoris
•indication for coronary artery bypass graft operation
•myocardial infarction within the last 3 months
•reduced left-ventricular systolic function \< 40 %

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: December 3, 2014Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment120

Start dateJul 2007

Last updatedDec 3, 2014

Condition

Stable Coronary Artery Disease Obesity Impaired Glucose Tolerance

Locations shown

University of Leipzig - heart center

Leipzig

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 3, 2014Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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