Evaluation of Effect of Combination With Telmisartan and Hydrochlorothiazide in Hypertensives Uncontrolled on Amlodipine

Exclusion Criteria

• •Secondary hypertension including renovascular hypertension with single kidney or bilateral stenosis
• •Administration of antihypertensives other than amlodipine
• •Cardiovascular disease (cerebral hemorrhage, cerebral infarction, TIA, angina, myocardial infarction, acute renal failure) occurs less than 6 months before start of the study
• •Serum creatinine \>= 2.0 mg/dl
• •Severe hypertension (systolic or diastolic blood pressure \>= 180/110 mmHg) or malignant hypertension (hypertensive organ damage is rapidly developing)
• •Chronic heart failure (NYHA class\>=III to VI)
• •Contraindication of telmisartan or hydrochlorothiazide
• •Hyper- (\>= 5.5 mEq/L) or hypo- (\<=3.5 mEq/l) potassemia
• •Untreated hyperuricemia or uncontrolled hyperuricemia (serum uric acid \>= 8.0 mg/dl)
• •Diabetic patients who require insulin therapy, uncontrolled diabetic patients (hemoglobin A1c \>=9.0%), or patients who possess the risk of hypoglycemic attack
• •Patients inadequate for the study