About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Back to clinical trial search

COMPLETEDPhase 4NCT00472966

Efficacy and Safety of Therapy With Tri-Luma® Cream in Sequence With Glycolic Acid Peels for Melasma

To determine the effectiveness and safety of sequential therapy with of Tri-Luma® Cream and a series of Glycolic Acid peels in treatment of moderate to severe melasma.

Lead sponsor: Galderma R&D•1 U.S. locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

Galderma R&D

To determine the efficacy and safety of sequential therapy with Fluocinolone acetonide 0.01%, Hydroquinone 4% and Tretinoin 0.05%, and a series of Glycolic Acid peels in the treatment of moderate to severe melasma.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Subjects diagnosed with moderate to severe melasma

Exclusion Criteria

•Subjects under treatment for a dermatologic condition, which may interfere with the safe evaluation of the study combination (e.g. eczema, psoriasis, severe sun-damage, dermatitis)
•Subjects with a diagnosis of skin cancer (BCE, SCC, Melanoma) in the areas to be treated

Related studies

COMPARISON OF A COSMETIC SERUM AND 4% HYDROQUINONE FOR TREATING MELASMA OVER 84 DAYS

NCT07071363 · Healthy, Melasma (Facial Melasma), and more

Development of Products Based on Secretom From Stem Cell Conditioned Medium for Melasma Therapy

NCT06516419 · Melasma

Enrolling By Invitation

Expert Consensus on the Clinical Management of Melasma: A Delphi Method Study

NCT07296549 · Melasma, Melasma (Facial Melasma)

Active Not RecruitingNA

Treatment and Prevention of Melasma Relapses by Using 1064nm 650 Microsecond Laser

NCT06644157 · Melasma

Not Yet RecruitingNA

Clinical Efficacy and Mechanisms of a Topical Azone-Tranexamic Acid-Aloe Polysaccharide Gel in the Treatment of Melasma

NCT07530016 · Melasma, Treatment of Stable Melasma, and more

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: July 29, 2022Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE4

Enrollment20

Start dateNov 2006

Last updatedJul 29, 2022

Condition

Locations shown

Skin Care Research, Inc.

Boca Raton, Florida

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 29, 2022Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions