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Lead
University of Cologne
Despite the adjuvant use of mitomycin C during trabeculectomy, short-term and long-term failures still occur. We investigate whether mitomycin C treatment during previous trabeculectomy induces P-glycoprotein expression. Expression of P-glycoprotein is analysed in surgically removed Tenon tissue using immunohistochemistry.
Age
8–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
patients with planned trabeculectomy for elevated eye pressure
one third of patients without previous trabeculectomy
two thirds of patients with previous trabeculectomy (one third with and one third without the use of mitomycin C)
You may not be if
patients not requiring surgery
patients with planned surgery for elevated eye pressure other than trabeculectomy
Clareo Health | Multidrug Resistance After Trabeculectomy With Mitomycin C
