Effect of Valsartan Compared to Enalapril on Sitting Systolic Blood Pressure in Children With High Blood Pressure

Exclusion Criteria

• •Renal artery stenosis
• •Current diagnosis of heart failure (NYHA Class II-IV).
• •MSSBP ≥ 25% above the 95th percentile
• •Second or third degree heart block without a pacemaker.
• •Concurrent potentially life threatening arrhythmia or symptomatic arrhythmia.
• •Clinically significant valvular heart disease.
• •Patient that demonstrates clinically significant ECG abnormalities other than those associated with left ventricular hypertrophy.
• •Previous solid organ transplantation except renal, liver or heart transplantation. Renal, liver or heart transplant must have occurred at least 6 months prior to enrollment. Patient must be on stable doses of immunosuppressive therapy for 3 months and deemed clinically stable by the investigator.