Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Novartis Pharmaceuticals
Age
6–17
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Male or female, ages 6-17, with a documented history of hypertension
Must be able to swallow a pill
Must be ≥ 18 kg or ≤160 kg
MSSBP (mean of 3 measurements) must be ≥ 95th percentile, for age, gender and height, at Visit 2 (randomization), by office blood pressure measurement
Patients who are eligible and able to participate in the study and whose parent(s)/guardian(s) consent in writing (written informed consent) to their doing so after the purpose and nature of the investigation has been clearly explained to them. (An assent will be required for some patients depending upon their age and local requirements regarding assents)
You may not be if
Renal artery stenosis
Current diagnosis of heart failure (NYHA Class II-IV).
MSSBP ≥ 25% above the 95th percentile
Second or third degree heart block without a pacemaker.
Concurrent potentially life threatening arrhythmia or symptomatic arrhythmia.
Clinically significant valvular heart disease.
Patient that demonstrates clinically significant ECG abnormalities other than those associated with left ventricular hypertrophy.
Previous solid organ transplantation except renal, liver or heart transplantation. Renal, liver or heart transplant must have occurred at least 6 months prior to enrollment. Patient must be on stable doses of immunosuppressive therapy for 3 months and deemed clinically stable by the investigator.
