Inoperable cancer of the pancreas.

Blood cell counts and blood chemistries in or near normal range.

Able to perform the activities of daily living.

A projected life expectancy of at least 2 months.

If female, neither pregnant nor nursing.

Willing to use contraceptives to prevent pregnancy.

No other serious illnesses.

No other active malignancy.

No serious infections.

No current other drug therapy for the cancer or steroid therapy.

Prior radiation is permitted as is chemotherapy given during radiation or to prevent relapse after surgical removal of the disease.

Safety Study of Imexon Plus Gemcitabine in Untreated Pancreatic Adenocarcinoma