Finding studies
Finding studies
Take this into the appointment.
Saves the questions and what to expect into your notes, next to the visit they belong to.
Lead
Hoosier Cancer Research Network
With
OUTLINE: This is a multi-center study. Paclitaxel 90 mg/m2 IV infusion over 1 hour days 1, 8 and 15 of 28 day cycle Plus Bevacizumab 10 mg/kg on days 1 and 15 of 28 day cycle. * 1 cycle = 28 days (4 weeks) * Disease assessments will be performed per RECIST every other cycle * After a minimum of 4 cycles or a maximum of 6 cycles of combination chemotherapy, bevacizumab monotherapy may continue until disease progression or intolerable side effects ECOG Performance Status 0 or 1 Hematopoietic: * White blood cell count \> 3,000 mm3 * Absolute neutrophil count (ANC) \> 1,500 mm3 * Platelet count \> 100,000 mm3 * International normalized ration (INR) of prothrombin time ≤ 1.2 * PTT no more than 5 seconds longer than the ULN Hepatic: * Bilirubin \< 1.5 x ULN * Aspartate aminotransferase (AST, SGOT) \< 2.5 x ULN Renal: * Urine protein:creatinine ratio \<1.0 Cardiovascular: * No history of myocardial infarction or angina pectoris/anginal equivalent in the last 6 months. Note: The patient may be on anti-anginal medications if the symptoms have been entirely controlled for greater than 6 months. * No history of uncontrolled congestive heart failure or uncontrolled hypertension
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted