Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sanofi
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Non-small cell bronchopulmonary cancer established by histological and/or cytological methods;
Advanced or metastatic disease (stage IIIB or IV);
At least one measurable lesion with one dimension (\>= 20 mm by CT scan or \>=10 mm by CT scan) outside of the irradiated area;
No prior chemotherapy;
Previous radiotherapy permitted as long as there has been a washout period of at least 4 weeks;
Age \>= 18 years old;
ECOG Performance Status (PS): 0-1;
Life expectancy \>3 months;
Hepatic and renal functions and blood count satisfactory:
* Blood counts: white blood cells \>= 3.0 x 10\^9/l, neutrophils \>= 1.5 x 10\^9/l, platelets \>= 150 x 10\^9/l, haemoglobin \>= 9 g/dl,
* Hepatic function: bilirubin within the limit of the normal upper value, aspartate transaminases (AST) or alanine transaminases (ALT) \<= 2.5 times the normal upper value
* Renal function: creatinine clearance (calculated according to Cockroft and Gault) \>= 40 ml/min;
Patients of reproductive age must use an effective contraceptive method;
Informed consent form signed before any procedure undertaken connected with the study
You may not be if
Pregnant or breastfeeding patient;
Past record of other cancers (excluding basocellular or epidermoid cutaneous carcinoma or cured carcinoma of the cervix);
Symptomatic cerebral or leptomeningeal metastases;
