Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Glostrup University Hospital, Copenhagen
With
Alpharma ApS
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease in the Central Nervous System (CNS). Acute optic neuritis is a common symptom of MS and is considered to have the same pathogenesis as MS, where autoimmune and inflammatory mechanisms lead to the progression of MS.
Statins reduce the cholesterol in blood and in addition have anti-inflammatory effects. From experimental data and results from pilot projects there is evidence that the statins perform anti-inflammatory and immune-modulatory effects and one can expect a beneficial outcome in the autoimmune inflammatory diseases after the treatment with statins.
Age
18–59
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Acute Optic Neuritis
Abnormal contrast sensitivity score (\>80)
Symptom duration maximum 4 weeks
Men and women between 18 and 59 years old
The patient must be physical and mental able to participate i this project with a 6 months of the duration
The patient must sign the written consent of the participation before the inclusion.
You may not be if
Optic neuritis earlier in the same eye
Pregnancy
Nursing
Fertile women who do not use contraception
Women who contemplate pregnancy in the duration of the study
Steroid treatment the last 4 weeks before the inclusion
Immune-supressor treatment the last 6 months before the inclusion
Active liver disease or continuous increase of liver enzymes (ASAT, ALAT)without known reason.
