Patients with recurrent or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL)

Prior treatment with at least 2 systemic chemotherapy regimens for CLL

Life expectancy of \>3 months

Adequate liver and kidney function

Absolute neutrophil count ≥500/mm3; platelets ≥50,000/dL; hemoglobin ≥9 g/dL

Willing to use accepted method of contraception during the course of the study

Negative pregnancy test (females)

Written informed consent

Safety Study of XL844 in Subjects With Chronic Lymphocytic Leukemia