Relation of Obesity With Frequency of Meals (MST 0557)

Exclusion Criteria

• •1. Diabetes mellitus
• •2. Chronic drug treatment for any medical condition like hypertension or hyperlipidemia, hyperthyroidism or taking weight control medications.
• •3. Inability to give informed consent.
• •4. Inability to give contact information including permanent residence or provide evidence of stable living environment for the study period.
• •5. Active weight reduction of more than 7 pounds in the last 3 months.
• •6. History of bleeding or blood clotting disorders.
• •7. Pregnancy or breast-feeding in the women.
• •8. History of anaphylaxis or anaphylactoid-like reaction as a result of food allergies.
• •9. HIV or hepatitis B and C positive subjects.
• •10. Subjects with hemoglobin \< 8.5 gm/dl.
• •11. Abnormal liver function test (ALT, AST, alkaline phosphate, LDH, GGT or total bilirubin).
• •12. Serum creatinine or BUN greater than the upper limit of the normal, serum albumin less than 3.5g/dl, or proteinuria 1+ or greater.
• •13. History of alcohol intake of more than 40 g/day.
• •14. Contraindications to magnetic resonance imaging (MRI) including pacemakers, surgical clips, metallic implants, neuromuscular- skeletal stimulators and internal orthopedic screws or rods.