Shorter Radiation Schedule for the Treatment of Prostate Cancer

Exclusion Criteria

• •PSA \> 40 mcg/L
• •previous therapy for carcinoma of the prostate other than biopsy or TURP, including patients previously on hormone therapy for treatment of their prostate cancer
• •prior or active malignancy other than non-melanoma skin cancer; or colon or thyroid cancer treated a minimum of five years prior to study entry and presumed cured
• •simulated volume exceeds 1000 cm3
• •previous pelvic radiotherapy
• •inflammatory bowel disease
• •serious non-malignant disease which would preclude radiotherapy or surgical biopsy
• •geographic inaccessibility for follow-up
• •psychiatric or addictive disorder which would preclude obtaining informed consent or adherence to protocol
• •unable to commence radiation therapy within 26 weeks of the date of last prostatic biopsy
• •failure to give informed consent to participate in the study