* Experimental design: multi-center, randomized (1:1), observer-blind, active-controlled study in 2 parallel groups with approximately:
* Study vaccine: full dose of Fluarix by IM administration.
* Control vaccine: full dose of Fluzone by IM administration.
* Two scheduled visits per subject at days 0 (visit 1) and 21(visit 2) with blood sample collected at each visit to evaluate the immune response. There will be a final contact with each subject 6 months after vaccination for safety follow up and study conclusion.
* Vaccination schedule: one IM injection at day 0.
* Type of study: Self contained.