Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Assistance Publique - Hôpitaux de Paris
It is a case-control multicenter study 185 caucasian pregnant women with preeclampsia and 185 paired controls without preeclampsia will be included.
The frequency of the V249I polymorphism in african black population will be determined by studying 200 subjects (100 cases and 100 controls).
The V249I polymorphism will be identified by PCR followed by enzyme digestion. Endothelial injury will be identified using three assays : von Willebrand factor, soluble VCAM-1 and thrombomodulin plasma levels.
CX3CR1 involvement in preeclampsia would have potential diagnostic and therapeutic consequences.
Age
Any age
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
cases: pregnant woman, evolutive pregnancy, preeclampsia, caucasian, consenting to the study
You may not be if
Cases:
multiple pregnancy, proteinuria \> 300 mg/24h before 21th gestation week.
